Pancreatic cancer is considered one of the most difficult challenges in the cancer world. It is often called a "silent killer" because its symptoms don't become apparent until the disease is quite advanced. A recent research report from Spain has sparked new discussion in the medical world. Scientists at Spain's National Cancer Research Center (CNIO) claim to have discovered an effective treatment against the most deadly form of pancreatic cancer.
What was the success of the research?
This team of scientists used a unique combination of three drugs in experiments on mice. The results of this combination were astonishing. In the lab, the mice's pancreatic tumors not only shrank but were completely eliminated. Most importantly, six years of follow-up after treatment showed no signs of cancer returning. Cancer drugs typically become ineffective over time because cancer cells replicate, but this new therapy didn't give the cells a chance to recover.
Why is pancreatic cancer dangerous?
The pancreas is a vital part of our body, producing enzymes for digestion and insulin to regulate blood sugar. Pancreatic ductal adenocarcinoma is the most dangerous type. This cancer is highly resistant to cancer cells and spreads rapidly to other parts of the body. Patients often discover the tumor when it becomes difficult to operate. Statistics indicate that approximately 85 percent of cases are diagnosed after the cancer has already spread.
What are its initial symptoms?
The best way to prevent this disease is to be aware of its symptoms. Early signs include pain in the upper abdomen that gradually radiates to the back. Unexplained weight loss, loss of appetite, and jaundice are also common symptoms. If a person suddenly develops diabetes or their urine becomes darker, these symptoms should not be ignored. Fatigue and digestive problems can also indicate this disease.
How the new therapy works
In this new research, scientists discovered that pancreatic cancer cells form a protective ring. CNIO's new therapy uses three different drugs that simultaneously attack various life processes in cancer cells, eliminating their resistance. This research has been published in the prestigious journal "Proceedings of the National Academy of Sciences," demonstrating its authenticity.
The way forward and challenges
While this success in mice is very encouraging, it will take time for its use in humans. The biological systems of mice differ from those of humans. This formula will now undergo clinical trials to ensure its safety and effectiveness in humans. Experts believe that if this trial is successful, it will be a revolutionary step in the history of oncology and could save thousands of lives.
