Obesity increases risk of type 2 diabetes, claims US study

Causes of Type 2 Diabetes: The risk of diabetes is higher in people who are obese than others. This claim is being made by American scientists. You can understand this connection between obesity and diabetes in detail in this article.

American scientists have discovered in a new study how obesity increases the risk of type 2 diabetes. This research has been done by the team of California-Los Angeles, which is trying to understand the relationship between obesity and diabetes through fat cells.

Studies have shown that obesity affects the production of ribosomal factors, an important cellular building block in the body, which makes the body's fat cells unable to function properly. As a result, excess energy accumulates in the body, which can lead to type 2 diabetes and other chronic diseases.

Impact of obesity

In this research, the team from the University of California-Los Angeles proved for the first time that obesity affects the production of ribosomal factors in the body. Ribosomal factors are essential for cells and their deficiency prevents fat stem cells from producing functional fat cells. This problem arises when there are not enough ribosomal factors in the body, due to which fat cells start increasing in size and the body's energy remains trapped. This energy accumulates and causes problems in the body, such as the development of type 2 diabetes.

Obesity problems

Dr. Claudio Villanueva, head of the study, says that fat tissue is often considered harmful to our health, but it plays an important role in controlling blood sugar levels in the body. They say that obese people have more amounts of fat tissue, which is not able to function properly, which reduces the body's metabolism and energy storage capacity. This condition becomes even more serious when fat stem cells do not function properly, causing energy to be stored in other places in the body. This accumulated excess energy can lead to problems such as fatty liver disease in the liver and atherosclerosis or stroke in the heart.

Experiments conducted on mice

In this study, obese and sugar-prone rats were used. The fat cells of these mice were four to five times larger than those of lean mice. These mice were then given a drug rosiglitazone. As a result, the levels of ribosomal factors returned to normal in the mice, enabling their fat stem cells to produce new and smaller fat cells. After this, the fat tissue of the mice was able to store energy better, and it also started producing key hormones that control metabolism. Although the mice remained obese after taking the drug, type 2 diabetes disappeared completely in them.

Signs of new treatment

This research indicates that understanding the complex relationship between obesity and type 2 diabetes may help, and may also aid in the development of new treatments. Scientists believe that these types of discoveries could open new avenues for treating type 2 diabetes and other chronic diseases.

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