Is it possible to treat diabetes with fat cells? Scientists discover unique connection between obesity and sugar!
Increasing cases of obesity and type 2 diabetes have worried scientists around the world. Meanwhile, scientists at the University of California-Los Angeles have revealed a big mystery through fat cells.
Increasing cases of obesity and type 2 diabetes have worried scientists around the world. Meanwhile, scientists at the University of California-Los Angeles have revealed a big mystery through fat cells. Researchers showed how obesity increases the risk of type 2 diabetes and how it may open up new avenues of treatment.
According to research, obesity disrupts the production of key cellular building blocks called ribosomal factors in the body. Due to the lack of these factors, fat stem cells are unable to make new, functional fat cells. As a result, energy gets trapped and fat cells increase in size. This process plays an important role in the development of type 2 diabetes. Dr. Claudio Villanueva, who led the research, said that fat tissue is often considered harmful, but it plays an important role in controlling blood sugar levels.
The new drug involved obese and sugar-prone mice. The fat cells of these mice were four to five times larger than those of lean mice. Scientists gave mice a drug called rosiglitazone, which returned their ribosomal factor to normal levels. This allowed their fat stem cells to produce newer, smaller and better functional fat cells. This procedure not only improved the metabolism of the mice, but also eliminated type 2 diabetes. Although the mice remained obese, their blood sugar levels returned to normal.
Future Expectations The study, published in Cell Reports, may provide a new direction in the treatment of type 2 diabetes and other chronic diseases. Scientists believe that by understanding the role of fat cells, effective treatment of diabetes can be possible in the future.
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