Insulin resistance in men after 45 years of age, increases risk of heart disease

Insulin resistance can increase the risk of aortic stenosis, a common heart disease in men over the age of 45, a new study has found.

The research was published in the journal Annals of Medicine and explores how insulin resistance can increase the risk of aortic stenosis that causes a heart attack. This study could open new avenues for treating and reducing the risk of heart disease.

Heart disease from insulin resistance

In this research, researchers from Kuopio University Hospital in Finland analyzed data from 10,144 men aged 45 to 73 years and found that men who had high insulin resistance had a higher risk of developing aortic stenosis. This condition arises when the arteries that supply blood from the heart to the body start shrinking.

Biomarker identification

The researchers identified several biomarkers related to insulin resistance in people affected by aortic stenosis, including fasting insulin, proinsulin and serum C-peptide. These biomarkers acted as important predictors of aortic stenosis, and this study made it clear that insulin resistance could be an important risk factor for aortic stenosis.

Health Management Required

Dr. Johanna Cuscisto, lead author of this research, said, "This new discovery highlights insulin resistance as an important risk factor for aortic stenosis."

Study findings

In this study, aortic stenosis was found in 116 men after an average follow-up period of 10.8 years. The results showed that insulin sensitivity could be improved by weight loss and regular exercise, which could help reduce the risk of the disease. Dr. Kuccistto has expressed the need for more studies based on this research so that effective measures can be found to avoid heart disease and other related health problems.