New Delhi: There are many reasons why it’s important to seek a doctor’s diagnosis as soon as possible. There are many causes for dementia symptoms and this may determine how to treat it. Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks. In most people with Alzheimer’s, symptoms first appear in their mid-60s. Alzheimer’s disease is the most common cause of dementia among older adults. The disease is named after Dr. Alois Alzheimer. In 1906, Dr. Alzheimer noticed changes in the brain tissue of a woman who had died of an unusual mental illness. Her symptoms included memory loss, language problems, and unpredictable behavior. After she died, he examined her brain and found many abnormal clumps and tangled bundles of fibers. These plaques and tangles in the brain are still considered some of the main features of Alzheimer’s disease. Another feature is the loss of connections between nerve cells (neurons) in the brain. Neurons transmit messages between different parts of the brain, and from the brain to muscles and organs in the body.
At present, no treatment can stop Alzheimer's disease, but now, a new study has accessible expect by showing that it is possible to reverse memory loss in the patients. Results from quantitative MRI and neuropsychological testing demonstrate unprecedented improvements in ten patients with early Alzheimer's disease (AD) or its precursors following treatment with a programmatic and personalized therapy. The study of 10 patients, which comes together from the Buck Institute for Research on Aging and the UCLA Easton Laboratories for Neurodegenerative Disease Research, is the first to impartially show that memory loss in patients can be upturned, and expansion continued, using a complex, 36-point therapeutic personalized program that involves complete changes in diet, brain stimulation, exercise, optimization of sleep, specific pharmaceuticals and vitamins, and multiple additional steps that affect brain chemistry.
Author Dale Bredesen conveyed that, all of these patients had either well-defined mild cognitive impairment (MCI), subjective cognitive impairment (SCI) or had been diagnosed with AD before beginning the program. They noted that patients who had to discontinue work were able to return to work and those under pressure at their jobs were able to get better their presentation. "Follow up testing showed some of the patients going from abnormal to normal. All but one of the ten patients included in the study are at genetic risk for AD, carrying at least one copy of the APOE4 allele. Five of the patients carry two copies of APOE4 which gives them a 10-12 fold increased risk of developing AD.